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Review
. 2006 Dec;25(6):864-7.
doi: 10.1016/j.immuni.2006.11.003.

Anergic B cells caught in the act

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Free article
Review

Anergic B cells caught in the act

Fritz Melchers. Immunity. 2006 Dec.
Free article

Abstract

Tolerance of B-lymphocytes to autoantigens is established by clonal deletion, receptor editing, and anergy. In this issue of Immunity, Merrell et al. (2006) have now identified that T3 "transitional" B cells in the spleen are not developmental intermediates but rather a major population of anergic B cells.

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