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. 2006 Oct;12(10):1580-3.
doi: 10.3201/eid1210.060529.

Chikungunya outbreaks caused by African genotype, India

Prasanna N Yergolkar  1 , Babasaheb V Tandale, Vidya A Arankalle, Padmakar S Sathe, A B Sudeep, Swati S Gandhe, Mangesh D Gokhle, George P Jacob, Supriya L Hundekar, Akhilesh C Mishra
Affiliations

Chikungunya outbreaks caused by African genotype, India

Prasanna N Yergolkar et al. Emerg Infect Dis. 2006 Oct.

Abstract

Chikungunya fever is reported in India after 32 years. Immunoglobulin M antibodies and virus isolation confirmed the cause. Phylogenic analysis based on partial sequences of NS4 and E1 genes showed that all earlier isolates (1963-1973) were Asian genotype, whereas the current and Yawat (2000) isolates were African genotype.

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Figures

Figure 1
Figure 1
Southern India, 3 states affected by chikungunya virus (October 2005–March 2006). Gray shading indicates area affected in each state.
Figure 2
Figure 2
Phylogenic analyses of partial NS4 (456 nt, panel A) and E1 (294 nt, panel B). Refer to Table 1 for the details of the isolates sequenced during this study. Percentage bootstrap support is indicated by the values at each node. The following sequences were obtained from GenBank database: E1, ROSS (AF490259); S27Africa (NC-004162); Tanz53 (AF192905); Africa76 (AF192903); CONGO1 (AY549583); CONGO2 (AY549581); CONGO3 (AY549579); Uganda82 (AF192907); Thai95 (AF192897); Thai96 (AF192900); Thai88 (AF192896); Thai62 (AF192908); Thai75 (AF192898); Thai78 (AF192899); Philip85 (AF192895); Indon85 (AF192894); Malay98A (AF394210); Malay98B (AF394211); Seneg83A (AY726732); ONY-UG96 (AF079456); Reuni06 (DQ443544); Seneg83B (AF192892); Niger64 (AF192893); Seneg66 (AF192891); NS1, UK/S27 (AF345888); ROSS (AF490259); S27Africa (NC-004162); Seneg83A (AY726732); ONY-UG96 (AF079456); and Reuni06 (DQ443544). O'nyong-nyong virus (AF079456) was used as an outgroup.
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References

    1. Jupp PG, McIntosh BM. Chikungunya virus disease. In: Monath TP, editor. The arboviruses: epidemiology and ecology. Vol. II. Boca Raton (FL): CRC Press; 1988. p. 137–57.
    1. Mackenzie JS, Chua KB, Daniels PW, Eaton BT, Field HE, Hall RA, et al. Emerging viral diseases of Southeast Asia and the Western Pacific. Emerg Infect Dis. 2001;7:497–504. 10.3201/eid0703.010303 - DOI - PMC - PubMed
    1. Kit LS. Emerging and re-emerging diseases in Malaysia. Asia Pac J Public Health. 2002;14:6–8. 10.1177/101053950201400103 - DOI - PubMed
    1. Laras K, Sukri NC, Larasati RP, Bangs MJ, Kosim R, Djauzi, et al. Tracking the re-emergence of epidemic chikungunya virus in Indonesia. Trans R Soc Trop Med Hyg. 2005;99:128–41. 10.1016/j.trstmh.2004.03.013 - DOI - PubMed
    1. Enserink M. Infectious diseases. Massive outbreak draws fresh attention to little-known virus. Science. 2006;311:1085. 10.1126/science.311.5764.1085a - DOI - PubMed