In vitro demonstration of an endothelial proliferative factor produced by neural cell lines
- PMID: 171768
- DOI: 10.1126/science.171768
In vitro demonstration of an endothelial proliferative factor produced by neural cell lines
Abstract
Cultured endothelial cells exhibit a six- to tenfold increase in thymidine labeling index in response to a soluble factor elaborated by clonal cell lines of neural origin. This factor, endothelial proliferation factor, appears to be a unique property of tumor cells and may mediate the vascularization of these neoplasms.
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