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. 2006;52(5):21-7.

[Neuroprotective effect of quercetin during experimental brain ischemia]

[Article in Ukrainian]
T M Kovalenko, I O Osadchenko, O M Tsupykov, T A Pivneva, A S Shalamaĭ, O O Moĭbenko, H H Skybo
  • PMID: 17176835

[Neuroprotective effect of quercetin during experimental brain ischemia]

[Article in Ukrainian]
T M Kovalenko et al. Fiziol Zh (1994). 2006.

Abstract

The neuroprotective action by water-soluble form of quercetin was examined in gerbils after transient forebrain ischemia. The animals were exposed to 7 min of bilateral common carotid artery occlusion. Hippocampal CA 1 area was examined 7 days after ischemia-reperfusion. The average density of CA1 pyramidal neurons and GFAP-positive glial cells were counted in sham operated group, in ischemic group and in the groups treated with water-soluble form of quercetin. It was shown that quercetin revealed protective effect by decreasing of delayed neuronal death and reducing reactive astrogliosis after ischemia-reperfusion.

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