Abnormal multifocal electroretinogram (mfERG) in ethambutol toxicity
- PMID: 17182409
- DOI: 10.1080/08820530600987454
Abnormal multifocal electroretinogram (mfERG) in ethambutol toxicity
Abstract
Objective: To report the abnormal multifocal electroretinogram (mfERG) findings in two cases of presumed ethambutol toxicity.
Design: Retrospective observational case series.
Participants: Two patients with ethambutol toxicity and visual loss.
Testing: Multifocal electroretinography.
Main outcome measure: Waveform measurements on multifocal electroretinography.
Results: Two patients with bilateral visual loss due to ethambutol toxicity underwent mfERG testing that disclosed both diffuse and central field loss compatible with retinal dysfunction as a contributing mechanism to the visual field loss.
Conclusion: Ethambutol toxicity affects not only the optic nerve but probably other retinal elements based upon abnormal mfERG findings.
Similar articles
-
Ethambutol neuroretinopathy.Semin Ophthalmol. 2007 Jul-Sep;22(3):141-6. doi: 10.1080/08820530701457134. Semin Ophthalmol. 2007. PMID: 17763233 Review.
-
Multifocal electroretinographic abnormalities in ethambutol-induced visual loss.J Neuroophthalmol. 2008 Dec;28(4):278-82. doi: 10.1097/WNO.0b013e31818e3ece. J Neuroophthalmol. 2008. PMID: 19145124
-
Multifocal electroretinography changes in patients on ethambutol therapy.Eye (Lond). 2009 Aug;23(8):1707-13. doi: 10.1038/eye.2008.361. Epub 2008 Dec 5. Eye (Lond). 2009. PMID: 19675572
-
Assessment of retinal function in patients with HIV without infectious retinitis by multifocal electroretinogram and automated perimetry.Retina. 2006 Oct;26(8):928-34. doi: 10.1097/01.iae.0000250009.60908.35. Retina. 2006. PMID: 17031295
-
Multifocal visual evoked potential, multifocal electroretinography, and optical coherence tomography in the diagnosis of subclinical loss of vision.Ophthalmol Clin North Am. 2004 Mar;17(1):89-105. doi: 10.1016/S0896-1549(03)00104-4. Ophthalmol Clin North Am. 2004. PMID: 15102515 Review.
Cited by
-
Ethambutol induces impaired autophagic flux and apoptosis in the rat retina.Dis Model Mech. 2015 Aug 1;8(8):977-87. doi: 10.1242/dmm.019737. Epub 2015 Jun 18. Dis Model Mech. 2015. PMID: 26092127 Free PMC article.
-
Risk factors for ethambutol optic toxicity.Int Ophthalmol. 2010 Feb;30(1):63-72. doi: 10.1007/s10792-009-9293-z. Epub 2009 Feb 11. Int Ophthalmol. 2010. PMID: 19205626
-
Reproducibility of the mfERG between instruments.Doc Ophthalmol. 2009 Aug;119(1):67-78. doi: 10.1007/s10633-009-9171-z. Epub 2009 Mar 26. Doc Ophthalmol. 2009. PMID: 19322597 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical