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Review
. 2007 Jan;92(1):F62-7.
doi: 10.1136/adc.2005.082297.

Management of fetal growth restriction

Affiliations
Review

Management of fetal growth restriction

M Alberry et al. Arch Dis Child Fetal Neonatal Ed. 2007 Jan.

Abstract

Fetal growth restriction (FGR) is challenging because of the difficulties in reaching a definitive diagnosis of the cause and planning management. FGR is associated not only with a marked increased risk in perinatal mortality and morbidity but also with long-term outcome risks. Combinations of fetal biometry, amniotic fluid volume, heart rate patterns, arterial and venous Doppler, and biophysical variables allow a comprehensive fetal evaluation of FGR. However, no evidence supports that the use of cardiotocography or the biophysical profile improves perinatal outcome. Therefore, obstetricians aim to identify fetuses with early FGR so delivery can be planned according to gestational age and severity of the condition. The balance of risks and the need for the availability of services mean that the involvement of neonatologists in FGR management is vital. In this review, the focus is on the pathophysiology and management of FGR caused by placental diseases.

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Conflict of interest statement

Competing interests: None declared.

References

    1. Odegard R A, Vatten L J, Nilsen S T.et al Preeclampsia and fetal growth. Obstet Gynecol 200096950–955. - PubMed
    1. Kupfermine M J, Peri H, Zwang E.et al High prevalence of the prothrombin gene mutation in women with intrauterine growth retardation, abruptio placentae and second trimester loss. Acta Obstet Gynecol Scand . 2000, 79963–967. - PubMed
    1. Snijders R J M, Sherrod C, Gosden C M.et al Fetal growth retardation associated malformations and chromosome abnormalities. Am J Obstet Gynecol 1993168547–555. - PubMed
    1. Tabano S, Alvino G, Antanazzo P. Placental LPL gene expression is increased in severe intrauterine growth‐restricted pregnancies. Paediatr Res 200659250–253. - PubMed
    1. Walker J J. Pre‐eclampsia. Lancet 20003561260–1265. - PubMed

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