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. 1991 Dec;59(12):4740-3.
doi: 10.1128/iai.59.12.4740-4743.1991.

Enhanced resistance against Listeria monocytogenes achieved by pretreatment with granulocyte colony-stimulating factor

N Shinomiya  1 , S Tsuru, Y Katsura, S Kayashima, K Nomoto
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Enhanced resistance against Listeria monocytogenes achieved by pretreatment with granulocyte colony-stimulating factor

N Shinomiya et al. Infect Immun. 1991 Dec.

Abstract

Phagocytosis, H2O2 production, Mac-1 expression, and in vivo elimination of Listeria monocytogenes were enhanced in granulocyte colony-stimulating factor (G-CSF)-treated mice. Transfer of polymorphonuclear leukocytes prolonged survival of mice infected with a lethal dose of L. monocytogenes. G-CSF augments the functions of polymorphonuclear leukocytes and thus plays a role in protection.

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