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Comment
. 2006 Dec 29;127(7):1306-7.
doi: 10.1016/j.cell.2006.12.013.

Retrograde control of neural circuit formation

Christopher D Deppmann  1 , David D Ginty
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Free article
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Retrograde control of neural circuit formation

Christopher D Deppmann et al. Cell. .
Free article

Abstract

Glial-derived neurotrophic factor (GDNF), secreted by skeletal muscle, triggers expression of the ETS transcription factor Pea3 in a subset of motor neurons in the spinal cord. In this issue, find that this retrograde GDNF-Pea3 signal controls dendrite patterning and assembly of a sensory-motor reflex circuit.

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