Comparative Study
doi: 10.1002/cbdv.200690000.
A pair of novel cytotoxic polyprenylated xanthone epimers from gamboges
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- PMID: 17193222
- DOI: 10.1002/cbdv.200690000
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Comparative Study
A pair of novel cytotoxic polyprenylated xanthone epimers from gamboges
Chem Biodivers.
2006 Jan.
Abstract
Two new polyprenylated xanthone epimers were isolated from gamboges of Garcinia hanburyi, and identified by detailed spectroscopic analysis as 30-hydroxygambogic acid (2a) and its (2S)-epimer 30-hydroxyepigambogic acid (2b). Both compounds exhibited significant cytotoxicities against the human leukemia K562/S and the corresponding doxorubicin-resistant K562/R cell lines (Table 2).
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