Autologous bone marrow transplantation/mobilization: a potential regenerative medicine for systemic degenerative disorders and healthy living

Abstract

Increased longevity is compromised for the quality of life due to prevalence of metabolic derangements and systemic degenerative disorders, as a result of lifestyle changes in modern days. In a craze to improve upon quality of life, use of pharmacological formulations aimed towards symptomatic treatment regimen is mandatory to manage variety of prevailing human ailments. However; these medicines have their own limitations and side effects, soliciting alternative therapy for better living. In light of preclinical and clinical studies on adult stem cells, bone marrow transplantation in healthy elderly individuals is likely to promote rejuvenation and prevent onset of degenerative disorders as well as cure prevailing disorders if any. Progress in unraveling pleuripotency of adult bone marrow stem cells compelled us to hypothesize that the only way to regain lost cells is to replace them with cells following the principle of 'Like begets Like' which may be achieved by autologous bone marrow transplantation/mobilization.