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Case Reports
. 2007 Oct;26(10):1745-8.
doi: 10.1007/s10067-006-0497-6. Epub 2007 Jan 3.

Sarcoidosis presenting as an osteolytic skull lesion: a case report and review of literature on skull sarcoidosis

Mario Fernández-Ruiz  1 , Juan-Manuel Guerra-Vales, Francisco-Javier Castelbón-Fernández, Jara Llenas-García, Jose-Luis Rodríguez-Peralto, Roberto López-Lancho, Irene Redondo-Marcos
Affiliations
Case Reports

Sarcoidosis presenting as an osteolytic skull lesion: a case report and review of literature on skull sarcoidosis

Mario Fernández-Ruiz et al. Clin Rheumatol. 2007 Oct.

Abstract

Bone sarcoidosis of the skull is an infrequent presentation of sarcoidosis. We describe a 51-year-old man who consulted due to inflammatory-appearing nodulation in the right supraorbital region. Images showed a solitary osteolytic lesion extending to soft tissues with increased scintigraphic uptake. The anatomopathological study revealed the presence of non-caseating epithelioid granulomas, compatible with sarcoidosis. Steroid treatment led to a marked remission of the lesion, without evidence of relapse during a follow-up period of 1 year. The literature dealing with skull sarcoidosis is reviewed.

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