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Case Reports
. 2007 Jan 3:2:2.
doi: 10.1186/1748-717X-2-2.

Bronchiolitis obliterans organizing pneumonia (BOOP) after thoracic radiotherapy for breast carcinoma

Robin Cornelissen  1 , Suresh Senan, Imogeen E Antonisse, Hauw Liem, Youke K Y Tan, Arjan Rudolphus, Joachim G J V Aerts
Affiliations
Case Reports

Bronchiolitis obliterans organizing pneumonia (BOOP) after thoracic radiotherapy for breast carcinoma

Robin Cornelissen et al. Radiat Oncol. .

Abstract

Common complications of thoracic radiotherapy include esophagitis and radiation pneumonitis. However, it is important to be aware of uncommon post-radiotherapy complications such as bronchiolitis obliterans organizing pneumonia (BOOP). We report on two patients with carcinoma of the breast who developed an interstitial lung disease consistent with BOOP. BOOP responds to treatment with corticosteroids and the prognosis is generally good despite of the need for long-term administration of corticosteroids as relapses can occur during tapering of steroids. This report provides guidelines for the evaluation and treatment of patients with pulmonary infiltrates after radiotherapy.

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Figures

Figure 1
Figure 1
CT shows patchy areas in the left lung and patchy areas in the middle lobe of the right lung.
Figure 2
Figure 2
CT shows an obvious improvement of the patchy infiltrates in the right lung after reintroduction of steroids.
See this image and copyright information in PMC

References

    1. Cottin V, Frognier R, Monnot H, Levy A, DeVuyst P, Cordier JF. Chronic eosinophilic pneumonia after radiation therapy for breast cancer. Eur Respir J. 2004;23:9–13. doi: 10.1183/09031936.03.00071303. - DOI - PubMed
    1. Dorr W, Bertmann S, Herrmann T. Radiation induced lung reactions in breast cancer therapy. Modulating factors and consequential effects. Strahlenther Onkol. 2005;181:567–573. doi: 10.1007/s00066-005-1457-9. - DOI - PubMed
    1. Oymak FS, Demirbas HM, Mavili E, Akgun H, Gulmez I, Demir R, Ozesmi M. Bronchiolitis obliterans organizing pneumonia. Clinical and roentgenological features in 26 cases. Respiration. 2005;72:254–262. doi: 10.1159/000085366. - DOI - PubMed
    1. Rosiello RA MWW. Radiation-induced lung injury. Clin Chest Med. 1990;11:65–71. - PubMed
    1. Bayle JY NP., Bejui-Thivolet F, et al Migratory organizing pneumonitis "primed" by radiation therapy. Eur Respir J. 1995;8:322–326. doi: 10.1183/09031936.95.08020322. - DOI - PubMed

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