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. 2007 Jan;35(Database issue):D511-4.
doi: 10.1093/nar/gkl972.

BRENDA, AMENDA and FRENDA: the enzyme information system in 2007

Jens Barthelmes  1 , Christian Ebeling, Antje Chang, Ida Schomburg, Dietmar Schomburg
Affiliations

BRENDA, AMENDA and FRENDA: the enzyme information system in 2007

Jens Barthelmes et al. Nucleic Acids Res. 2007 Jan.

Abstract

The BRENDA (BRaunschweig ENzyme DAtabase) enzyme information system (http://www.brenda.uni-koeln.de) is the largest publicly available enzyme information system worldwide. The major parts of its contents are manually extracted from primary literature. It is not restricted to specific groups of enzymes, but includes information on all identified enzymes irrespective of the enzyme's source. The range of data encompasses functional, structural, sequence, localisation, disease-related, isolation, stability information on enzyme and ligand-related data. Each single entry is linked to the enzyme source and to a literature reference. Recently the data repository was complemented by text-mining data in AMENDA (Automatic Mining of ENzyme DAta) and FRENDA (Full Reference ENzyme DAta). A genome browser, membrane protein prediction and full-text search capacities were added. The newly implemented web service provides instant access to the data for programmers via a SOAP (Simple Object Access Protocol) interface. The BRENDA data can be downloaded in the form of a text file from the beginning of 2007.

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Figures

Figure 1
Figure 1
Organism coverage in BRENDA data.
Figure 2
Figure 2
BRENDA Genome Explorer showing a genome alignment for Escherichia coli erythronate-4-phosphate dehydrogenase, EC 1.1.1.290 (excerpt).
See this image and copyright information in PMC

References

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