Comparative Study
doi: 10.1016/j.exppara.2006.11.002.
Epub 2007 Jan 4.
Histone H1 regulates chromatin condensation in Leishmania parasites
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- PMID: 17207482
- DOI: 10.1016/j.exppara.2006.11.002
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Comparative Study
Histone H1 regulates chromatin condensation in Leishmania parasites
Exp Parasitol.
2007 May.
Abstract
We investigated the functional role of the Leishmania histone H1 and demonstrate for the first time that addition of histone H1 has a strong effect on microccocal digestion, chromatin condensation of parasite nuclei and that its overexpression can modulate parasite infectivity in vivo.
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