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Comparative Study
. 2007 May;116(1):83-7.
doi: 10.1016/j.exppara.2006.11.002. Epub 2007 Jan 4.

Histone H1 regulates chromatin condensation in Leishmania parasites

Slavica Masina  1 , Haroun Zangger, Denis Rivier, Nicolas Fasel
Affiliations
Comparative Study

Histone H1 regulates chromatin condensation in Leishmania parasites

Slavica Masina et al. Exp Parasitol. 2007 May.

Abstract

We investigated the functional role of the Leishmania histone H1 and demonstrate for the first time that addition of histone H1 has a strong effect on microccocal digestion, chromatin condensation of parasite nuclei and that its overexpression can modulate parasite infectivity in vivo.

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