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. 2007 Jan;7(1):45-50.
doi: 10.1021/nl0619103.

DNA nucleoside interaction and identification with carbon nanotubes

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DNA nucleoside interaction and identification with carbon nanotubes

Sheng Meng et al. Nano Lett. 2007 Jan.

Abstract

We investigate the interaction of individual DNA nucleosides with a carbon nanotube (CNT) in vacuum and in the presence of external gate voltage. We propose a scheme to discriminate between nucleosides on CNTs based on measurement of electronic features through a local probe such as scanning tunneling spectroscopy. We demonstrate through quantum mechanical calculations that these measurements can achieve 100% efficiency in identifying DNA bases. Our results support the practicality of ultrafast DNA sequencing using electrical measurements.

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