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Clinical Trial
. 1991 Dec;23(6):2763-6.

Comparative study of cyclosporine and FK 506 dosage requirements in adult and pediatric orthotopic liver transplant patients

A B Jain  1 , J J Fung, A G Tzakis, R Venkataramanan, K Abu-Elmagd, M Alessiani, J Reyes, W Irish, V Warty, S Mehta, et al.
Affiliations
Clinical Trial

Comparative study of cyclosporine and FK 506 dosage requirements in adult and pediatric orthotopic liver transplant patients

A B Jain et al. Transplant Proc. 1991 Dec.
No abstract available

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Figures

Fig 1
Fig 1
Demonstrates prolonged use IV treatment in CyA group of patients with need to combine IV and oral treatment, whereas in FK 506 group of patients there is no need for combined IV and oral treatment.
Fig 2
Fig 2
Mean ± SD oral dose of CyA in adults (□) and children (○) over weeks 5 to 52 posttransplant.
Fig 3
Fig 3
(A) Direct comparison of mean oral dose of CyA in adults (solid bar) and children (hatched bar) from weeks 1 to 52 post-transplant. (B) Compares mean FK 506 oral dose in adults and pediatric OLTx for the same period.
Fig 4
Fig 4
Mean oral dose of FK 506 In adults (□) and pediatric OLTx (○) WIth SD over Weeks 5 to 52 posttransplant.
Fig 5
Fig 5
Median CyA whole-blood trough levels for adults and pediatric OLTx from weeks 1 to 52 posttransplant.
Fig 6
Fig 6
Median FK 506 plasma trough levels for adults and children OLTx from weeks 1 to 52 posttransplant.
See this image and copyright information in PMC

References

    1. Todo S, Fung JJ, Tzakis A, et al. Transplant Proc. 1991;23(1):1397. - PubMed
    1. Burckart GJ, Starzl T, Williams L, et al. Transplant Proc. 1985;17:1172. - PMC - PubMed
    1. Mehta M, Venkataramanan R, Burckart G, et al. Br J Clin Pharmacol. 1988;25:579. - PMC - PubMed
    1. Jain A, Venkataramanan R, Cadoff E, et al. Transplant Proc. 1990;22:57. - PMC - PubMed
    1. Venkataramanan R, Jain A, Warty VW, et al. Transplant Proc. 1991;23:931. - PMC - PubMed

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