Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1991 Dec;23(6):2771-4.

Strategy of FK 506 therapy in liver transplant patients: effect of graft function

K M Abu-Elmagd  1 , J J Fung, M Alessiani, A Jain, S Takaya, R Venkataramanan, V S Warty, W Shannon, S Todo, A Tzakis, et al.
Affiliations

Strategy of FK 506 therapy in liver transplant patients: effect of graft function

K M Abu-Elmagd et al. Transplant Proc. 1991 Dec.
No abstract available

PubMed Disclaimer

Figures

Fig 1
Fig 1
Effect of postoperative liver function on FK 506 doses, plasma levels, and kidney function. Note that the highest plasma levels despite the lowest doses were in the patients with early unsatisfactory graft function. Meanwhile, four class III patients and five class IV patients required postoperative dialysis for some time.
Fig 2
Fig 2
Scatter plots for the actual values of simultaneously determined serum bilirubin, FK 506 plasma level, and drug dose on log10 scale for all recipients. Serum bilirubin has a significant positive correlation with FK 506 plasma levels and inverse correlation with FK 506 doses. With r value of 0.158, there was a significant (P = .0007) correlation between FK 506 doses and levels.
See this image and copyright information in PMC

References

    1. Abu-Elmagd K, Fung JJ, Alessiani M, et al. Transplantation. 1991;52:71. - PMC - PubMed
    1. Tamura K, Kobayashi M, Hashimoto K, et al. Transplant Proc. 1987;19 suppl:23. - PubMed
    1. Venkataramanan R, Jain A, Cadoff E, et al. Transplant Proc. 1990;22:52. - PMC - PubMed
    1. Jain AB, Venkataramanan R, Cadoff E, et al. Transplant Proc. 1990;22:57. - PMC - PubMed
    1. Ptachcinski RJ, Venkataramanan R, Burckard GJ. Clin Pharmacokinet. 1986;11:107. - PubMed

Publication types

LinkOut - more resources