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Review
. 2007 Jan;60(1):18-26.
doi: 10.1136/jcp.2005.035592.

Distinguishing diabetic nephropathy from other causes of glomerulosclerosis: an update

K O Alsaad  1 , A M Herzenberg
Affiliations
Review

Distinguishing diabetic nephropathy from other causes of glomerulosclerosis: an update

K O Alsaad et al. J Clin Pathol. 2007 Jan.

Abstract

Diabetic nephropathy is a common cause of end-stage renal disease worldwide. It is characterised by diffuse or nodular glomerulosclerosis, afferent and efferent hyaline arteriolosclerosis, and tubulointerstitial fibrosis and atrophy. Diffuse and nodular diabetic glomerulosclerosis share similar histological features with other clinical conditions. Immunofluorescence and electron microscopy studies, and clinicopathological correlation are essential to differentiate diabetic nephropathy from other conditions that result in diffuse and nodular glomerulosclerosis.

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Conflict of interest statement

Competing interests: None declared.

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