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Comparative Study
. 2007 Jan;24(1):26-33.
doi: 10.1111/j.1540-8175.2007.00346.x.

Correlation of the myocardial performance index with conventional echocardiographic indices of systolic and diastolic function: a study in cardiac surgical patients

Glenn S Murphy  1 , Jesse H Marymont, Joseph W Szokol, Michael J Avram, Jeffery S Vender
Affiliations
Comparative Study

Correlation of the myocardial performance index with conventional echocardiographic indices of systolic and diastolic function: a study in cardiac surgical patients

Glenn S Murphy et al. Echocardiography. 2007 Jan.

Abstract

Background: The aim of this investigation was to compare the myocardial performance index (MPI), a Doppler-derived parameter of global ventricular function, with standard echocardiographic measures of systolic and diastolic function in patients undergoing coronary artery bypass graft (CABG) surgery.

Methods: Complete two-dimensional and Doppler examinations were performed on 46 CABG patients after induction of anesthesia (baseline), 15 minutes postcardiopulmonary bypass (CPB), and at the end of the surgical procedure.

Results: A strong inverse correlation between MPI and both fractional area change (adjusted r(2)= 0.588-0.802) and ejection fraction (adjusted r(2)= 0.576-0.656, both P < 0.001) of the left ventricle was observed throughout the intraoperative period. Following CPB, a weaker correlation was observed between MPI and overall diastolic heart function classification (adjusted r(2)= 0.224-0.268, P <0.001). Weak, though statistically significant, correlations were observed between MPI and deceleration time (P < 0.05), peak atrial reversal (AR) wave velocity (P < or =0.002), and duration of the AR wave (P < 0.05).

Conclusion: Our data suggest that the MPI correlates well with standard echocardiographic measures of systolic function and modestly well with overall diastolic heart function classification. The MPI may be a useful, complementary marker of global left ventricular function in patients undergoing CABG surgery.

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