Review
doi: 10.1007/978-3-540-34891-7_24.
TRP channels of the pancreatic beta cell
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- PMID: 17217070
- DOI: 10.1007/978-3-540-34891-7_24
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Review
TRP channels of the pancreatic beta cell
Handb Exp Pharmacol.
2007.
Abstract
Orchestrated ion fluctuations within pancreatic islets regulate hormone secretion and maybe essential to processes such as apoptosis. A diverse set of ion channels allows for islet cells to respond to a variety of signals and dynamically regulate hormone secretion and glucose homeostasis (reviewed by Houamed et al. 2004). This chapter focuses on transient receptor potential (TRP)-related channels found within the beta cells of the islet and reviews their roles in both insulin secretion and apoptosis.
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