doi: 10.1016/j.cell.2006.12.018.
A mouse for all reasons
- PMID: 17218247
- DOI: 10.1016/j.cell.2006.12.018
Item in Clipboard
A mouse for all reasons
Cell.
.
Free article
Abstract
Three major mouse knockout programs are underway worldwide, working together to mutate all protein-encoding genes in the mouse using a combination of gene trapping and gene targeting in mouse embryonic stem (ES) cells. Although the current emphasis is on production of this valuable resource, there are significant efforts to facilitate program coordination, to enhance the availability of this resource, and to plan for future efforts in mouse genetics research.
Comment in
-
A new partner for the international knockout mouse consortium.Cell. 2007 Apr 20;129(2):235. doi: 10.1016/j.cell.2007.04.007. Cell. 2007. PMID: 17448981 No abstract available.
Similar articles
-
A review of current large-scale mouse knockout efforts.Genesis. 2010 Feb;48(2):73-85. doi: 10.1002/dvg.20594. Genesis. 2010. PMID: 20095055 Review.
-
Gene trapping in embryonic stem cells.Methods Enzymol. 2006;420:136-62. doi: 10.1016/S0076-6879(06)20008-9. Methods Enzymol. 2006. PMID: 17161697
-
EUCOMM--the European conditional mouse mutagenesis program.Brief Funct Genomic Proteomic. 2007 Sep;6(3):180-5. doi: 10.1093/bfgp/elm022. Epub 2007 Oct 29. Brief Funct Genomic Proteomic. 2007. PMID: 17967808
-
Generation of a mouse mutant by oligonucleotide-mediated gene modification in ES cells.Nucleic Acids Res. 2006;34(21):e147. doi: 10.1093/nar/gkl896. Epub 2006 Nov 16. Nucleic Acids Res. 2006. PMID: 17142234 Free PMC article.
-
Gene trap mutagenesis.Handb Exp Pharmacol. 2007;(178):129-47. doi: 10.1007/978-3-540-35109-2_6. Handb Exp Pharmacol. 2007. PMID: 17203654 Review.
Cited by
-
A novel 3D mouse embryo atlas based on micro-CT.Development. 2012 Sep;139(17):3248-56. doi: 10.1242/dev.082016. Development. 2012. PMID: 22872090 Free PMC article.
-
Mutant mice derived by ICSI of evaporatively dried spermatozoa exhibit expected phenotype.Reproduction. 2012 Apr;143(4):449-53. doi: 10.1530/REP-12-0005. Epub 2012 Jan 24. Reproduction. 2012. PMID: 22274886 Free PMC article.
-
Striking Immune Phenotypes in Gene-Targeted Mice Are Driven by a Copy-Number Variant Originating from a Commercially Available C57BL/6 Strain.Cell Rep. 2016 May 31;15(9):1901-9. doi: 10.1016/j.celrep.2016.04.080. Epub 2016 May 19. Cell Rep. 2016. PMID: 27210752 Free PMC article.
-
NEXMIF/KIDLIA Knock-out Mouse Demonstrates Autism-Like Behaviors, Memory Deficits, and Impairments in Synapse Formation and Function.J Neurosci. 2020 Jan 2;40(1):237-254. doi: 10.1523/JNEUROSCI.0222-19.2019. Epub 2019 Nov 8. J Neurosci. 2020. PMID: 31704787 Free PMC article.
-
PBmice: an integrated database system of piggyBac (PB) insertional mutations and their characterizations in mice.Nucleic Acids Res. 2008 Jan;36(Database issue):D729-34. doi: 10.1093/nar/gkm790. Epub 2007 Oct 11. Nucleic Acids Res. 2008. PMID: 17932058 Free PMC article.
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
