Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2007 Jan 12;128(1):20-1.
doi: 10.1016/j.cell.2006.12.022.

Polo delivers a PICH to the kinetochore

Tim J Yen  1
Affiliations
Free article
Comment

Polo delivers a PICH to the kinetochore

Tim J Yen. Cell. .
Free article

Abstract

In this issue, Baumann et al. (2007) identify a helicase PICH that localizes to "threads" that remain connected between sister kinetochores after they have separated in anaphase. These threads are thought to be catenated centromeric DNA. PICH contributes to the mitotic checkpoint by recruiting Mad2 to kinetochores and is proposed to regulate checkpoint signaling by monitoring tension at centromeres.

PubMed Disclaimer

Comment on

LinkOut - more resources