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Comment
. 2007 Jan 12;315(5809):187; author reply 187.
doi: 10.1126/science.1130571.

Comment on "A common genetic variant is associated with adult and childhood obesity"

Dieter Rosskopf  1 , Alexa Bornhorst, Christian Rimmbach, Christian Schwahn, Alexander Kayser, Anne Krüger, Grietje Tessmann, Ingrid Geissler, Heyo K Kroemer, Henry Völzke
Affiliations
Comment

Comment on "A common genetic variant is associated with adult and childhood obesity"

Dieter Rosskopf et al. Science. .

Abstract

Contrary to the findings of Herbert et al. (Reports, 14 April 2006, p. 279), homozygous carriers of the C allele of the rs7566605 variant near the INSIG2 gene did not exhibit a significantly increased risk for obesity in a large population-based cross-sectional German study. A subgroup analysis, however, revealed that this allele significantly increased the risk for obesity in already overweight individuals.

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Comment on

  • A common genetic variant is associated with adult and childhood obesity.
    Herbert A, Gerry NP, McQueen MB, Heid IM, Pfeufer A, Illig T, Wichmann HE, Meitinger T, Hunter D, Hu FB, Colditz G, Hinney A, Hebebrand J, Koberwitz K, Zhu X, Cooper R, Ardlie K, Lyon H, Hirschhorn JN, Laird NM, Lenburg ME, Lange C, Christman MF. Herbert A, et al. Science. 2006 Apr 14;312(5771):279-83. doi: 10.1126/science.1124779. Science. 2006. PMID: 16614226

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