Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2007 Jan 13;334(7584):76-8.
doi: 10.1136/bmj.39064.406389.94.

When should antiretroviral therapy for HIV be started?

Affiliations
Review

When should antiretroviral therapy for HIV be started?

Andrew N Phillips et al. BMJ. .

Abstract

Treatments for HIV have advanced rapidly over the past decade. Andrew Phillips and colleagues argue that we should re-evaluate the timing of treatment in the light of new knowledge

PubMed Disclaimer

Conflict of interest statement

Competing interests: All authors have at some point received funding (personally or for research) from one or more companies producing drugs for HIV.

Figures

None
Risk of AIDS over time according to CD4 count at start of antiretroviral therapy. Adapted from Egger et al

References

    1. Burman WJ, Reves RR, Cohn DL. The case for conservative management of early HIV disease. JAMA 1998;280:93-5. - PubMed
    1. Holmberg SD, Palella FJ, Lichtenstein KA, Havlir DV. The case for earlier treatment of HIV infection. Clin Infect Dis 2004;39:1699-704. - PubMed
    1. Walker BD, Basgoz N. Treat HIV-1 infection like other infections—treat it. JAMA 1998;280:91-3. - PubMed
    1. Phillips AN, Cozzi Lepri A, Lampe F, Johnson M, Sabin CA. When should antiretroviral therapy be started for HIV infection? Interpreting the evidence from observational studies. AIDS 2003;17:1863-9. - PubMed
    1. Maini MK, Gilson RJC, Chavda N, Gill S, Fakoya A, Ross EJ, et al. Reference ranges and sources of variability of CD4 counts in HIV-seronegative women and men. Genitourinary Med 1996;72:27-31. - PMC - PubMed

MeSH terms