[The value of FDG PET/CT, ultrasound and CT in diagnosing recurrent ovarian carcinoma]

Abstract

The diagnosis of recurrent ovarian cancer can be complicated and variable sensitivities, specificities and accuracies have been reported for integrated positron emission tomography and computed tomography (PET/CT). The aim of the study was to evaluate the sensitivity, specificity and accuracy of PET/CT, ultrasound and CT in the diagnosing recurrent ovarian cancer.

Materials and methods: 27 women in the follow-up after cytoreductive surgery and chemotherapy of ovarian cancer, underwent ultrasound, CT and PET/CT to assess for possible recurrence.

Results: Recurrence of ovarian cancer was detected in 22 patients (laparotomy or cytology of ascites or pleural effusion). 5 disease-free patients were followed-up for 8-14 months. FDG-PET, ultrasound and CT had sensitivities of 81,82%, 45,45%, 55.56%, specificities of 60%, 60%, 60% and accuracies 77,78%, 48,15%, 52,17% respectively.

Conclusions: 1. FDG PET/CT is a useful technique to in diagnosing recurrent ovarian cancer. 2. PET/CT depicts/detects recurrent ovarian cancer with higher diagnostic accuracy comparing to the standard imaging and provides the chance to detect disease at an earlier stage during follow-up.