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. 2007 Mar;75(3):1537-9.
doi: 10.1128/IAI.01938-06. Epub 2007 Jan 12.

Role of unsaturated fatty acid biosynthesis in virulence of Streptococcus mutans

Elizabeth M Fozo  1 , Kathy Scott-Anne, Hyun Koo, Robert G Quivey Jr
Affiliations

Role of unsaturated fatty acid biosynthesis in virulence of Streptococcus mutans

Elizabeth M Fozo et al. Infect Immun. 2007 Mar.

Abstract

An insertionally inactivated fabM strain of Streptococcus mutans does not produce unsaturated membrane fatty acids and is acid sensitive (E. M. Fozo and R. G. Quivey, Jr., J. Bacteriol. 186:4152-4158, 2004). In this study, the strain was shown to be poorly transmissible from host to host. Animals directly infected with the fabM strain exhibited fewer and less severe carious lesions than those observed in the wild-type strain.

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Figures

FIG. 1.
FIG. 1.
Transmission experiment outline. SDV, sialoacroadenitis virus.
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