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Review
. 2007 Apr;103(4):560-9.
doi: 10.1016/j.tripleo.2006.10.004. Epub 2007 Jan 12.

The antimicrobial effects of root canal irrigation and medication

Ikhlas El Karim  1 , John Kennedy, David Hussey
Affiliations
Review

The antimicrobial effects of root canal irrigation and medication

Ikhlas El Karim et al. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Apr.

Abstract

The role of microorganisms in the development and maintenance of pulpal and periapical inflammation have been well documented. The success of root canal treatment largely depends on the elimination of microbial contamination from the root canal system. Although mechanical instrumentation of root canals can reduce bacterial population, effective elimination of bacteria cannot be achieved without the use of antimicrobial root canal irrigation and medication. This review will discuss the antimicrobial effects of the known root canal irrigants and medicaments and explore future developments in the field.

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