Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1991 Dec 30;109(2):255-8.
doi: 10.1016/0378-1119(91)90617-k.

cDNA encoding murine FK506-binding protein (FKBP): nucleotide and deduced amino acid sequence

P A Nelson  1 , J A Lippke, M A Murcko, S L Rosborough, D A Peattie
Affiliations

cDNA encoding murine FK506-binding protein (FKBP): nucleotide and deduced amino acid sequence

P A Nelson et al. Gene. .

Abstract

A FKBP cDNA encoding murine FK506 binding protein (FKBP) has been cloned, and its complete nucleotide sequence has been determined. The open reading frame within the 1556-bp cDNA segment encodes an 108 amino acid (aa) protein that differs from the human FKBP by three aa and from the bovine FKBP by five aa. Molecular modeling of the protein places the aa substitutions at positions not directly involved in drug binding or interaction with the potential drug target protein, calcineurin A.

PubMed Disclaimer