Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2007 Mar;104(3):747-52.
doi: 10.1016/j.ygyno.2006.11.008. Epub 2007 Jan 16.

Ovarian neuroendocrine carcinoma, non-small cell type, associated with serous carcinoma

Yoo Duk Choi  1 , Ji Shin Lee, Chan Choi, Chang Soo Park, Jong Hee Nam
Affiliations
Case Reports

Ovarian neuroendocrine carcinoma, non-small cell type, associated with serous carcinoma

Yoo Duk Choi et al. Gynecol Oncol. 2007 Mar.

Abstract

Background: Neuroendocrine carcinoma of the non-small cell type of the ovary is a rare aggressive tumor, interestingly associated with either a surface epithelial tumor or teratoma.

Case: A 71-year-old woman presented with a pelvic mass and underwent a total abdominal hysterectomy with a bilateral salpingo-oophorectomy. Pathology examination showed a 6.5 cm in greatest dimension ovarian tumor composed of neuroendocrine carcinoma of the non-small cell type and serous carcinoma. Immunohistochemical studies including keratin 7, WT-1, and neuroendocrine markers demonstrated differences in the two components. Microsatellite instability (MSI) analysis using five polymorphic markers also showed a different pattern in the two components.

Conclusion: This is the first report of an ovarian neuroendocrine carcinoma, non-small cell type, associated with a serous carcinoma. Immunohistochemistry and MSI are very helpful in making a definite diagnosis.

PubMed Disclaimer

Publication types