Poor-prognosis germ cell tumors: we have not yet crossed the finish line

Editorial

David J Vaughn et al. J Clin Oncol. 2007.

. 2007 Jan 20;25(3):239-40.

doi: 10.1200/JCO.2006.07.6380.

No abstract available

Comment on

Phase III randomized trial of conventional-dose chemotherapy with or without high-dose chemotherapy and autologous hematopoietic stem-cell rescue as first-line treatment for patients with poor-prognosis metastatic germ cell tumors.
Motzer RJ, Nichols CJ, Margolin KA, Bacik J, Richardson PG, Vogelzang NJ, Bajorin DF, Lara PN Jr, Einhorn L, Mazumdar M, Bosl GJ. Motzer RJ, et al. J Clin Oncol. 2007 Jan 20;25(3):247-56. doi: 10.1200/JCO.2005.05.4528. J Clin Oncol. 2007. PMID: 17235042 Clinical Trial.

Poor prognosis germ cell tumors of the testes: improved results with high dose regimens.
Ozols RF. Ozols RF. Prog Clin Biol Res. 1988;269:419-27. Prog Clin Biol Res. 1988. PMID: 2455910 Clinical Trial. No abstract available.
The chemotherapy of disseminated testicular non-seminomatous germ cell tumors and the clinical research of the EORTC Genitourinary Group.
Stoter G, Denis L. Stoter G, et al. Acta Urol Belg. 1985;53(2):428-40. Acta Urol Belg. 1985. PMID: 2409785 Review. English, French. No abstract available.
First-line chemotherapy of non-seminomatous germ cell tumors(NSGCTs).
Pliarchopoulou K, Pectasides D. Pliarchopoulou K, et al. Cancer Treat Rev. 2009 Nov;35(7):563-9. doi: 10.1016/j.ctrv.2009.05.004. Epub 2009 Jul 2. Cancer Treat Rev. 2009. PMID: 19576697 Review.
Germ-cell tumors.
De Giorgi U, Pedrazzoli P, Rosti G; Italian Germ-Cell Cancer Group; Gruppo Italiano per il Trapianto di Midollo Osseo, Cellule Staminali Emopoietiche e Terapia Cellulare. De Giorgi U, et al. N Engl J Med. 2007 Oct 25;357(17):1773; author reply 1773-4. N Engl J Med. 2007. PMID: 17969230 No abstract available.
Germ-cell tumors.
Lorch A, Beyer J, Bokemeyer C. Lorch A, et al. N Engl J Med. 2007 Oct 25;357(17):1772-3; author reply 1773-4. N Engl J Med. 2007. PMID: 17969228 No abstract available.