Review
doi: 10.1016/0167-5699(91)90018-O.
Naturally-occurring peptide antigens derived from the MHC class-I-restricted processing pathway
Affiliations
- PMID: 1723878
- DOI: 10.1016/0167-5699(91)90018-O
Item in Clipboard
Review
Naturally-occurring peptide antigens derived from the MHC class-I-restricted processing pathway
Immunol Today.
1991 Dec.
Abstract
The extraction of naturally-processed peptides from MHC class I glycoproteins has paved the way for a major advance in the understanding of the antigen processing pathway that ultimately induces cytotoxic T-cell responses. Here, Olaf Rötzschke and Kirsten Falk review these new developments and discuss their findings in terms of a novel hypothesis of MHC class-I-restricted processing.
Similar articles
-
The cell biology of antigen processing.Crit Rev Biochem Mol Biol. 1991;26(5-6):439-73. doi: 10.3109/10409239109086790. Crit Rev Biochem Mol Biol. 1991. PMID: 1722142 Review.
-
Pathways of viral antigen processing and presentation to CTL: defined by the mode of virus entry?Immunol Today. 1989 Feb;10(2):45-8. doi: 10.1016/0167-5699(89)90303-4. Immunol Today. 1989. PMID: 2665772 Review.
-
Processing of a minimal antigenic peptide alters its interaction with MHC molecules.Nature. 1988 Feb 11;331(6156):538-40. doi: 10.1038/331538a0. Nature. 1988. PMID: 2448649
-
Cytosolic targeting of hen egg lysozyme gives rise to a short-lived protein presented by class I but not class II major histocompatibility complex molecules.Eur J Immunol. 1991 Mar;21(3):761-9. doi: 10.1002/eji.1830210332. Eur J Immunol. 1991. PMID: 2009914
-
The structure and function of MHC molecules. Possible implications for the control of tumor growth by MHC-restricted T cells.Semin Cancer Biol. 1991 Oct;2(5):275-82. Semin Cancer Biol. 1991. PMID: 1773044 Review.
Cited by
-
Structural requirements for binding of an immunodominant myelin basic protein peptide to DR2 isotypes and for its recognition by human T cell clones.J Exp Med. 1994 Jan 1;179(1):279-90. doi: 10.1084/jem.179.1.279. J Exp Med. 1994. PMID: 7505801 Free PMC article.
-
Interleukin-4 plus tumor necrosis factor alpha augments the antigenicity of melanoma cells.Cancer Immunol Immunother. 1993 Nov;37(6):378-84. doi: 10.1007/BF01526794. Cancer Immunol Immunother. 1993. PMID: 8242663 Free PMC article.
-
Tumour-specific cytotoxic T lymphocyte activity in Th2-type Sézary syndrome: its enhancement by interferon-gamma (IFN-gamma) and IL-12 and fluctuations in association with disease activity.Clin Exp Immunol. 1998 Jun;112(3):403-9. doi: 10.1046/j.1365-2249.1998.00599.x. Clin Exp Immunol. 1998. PMID: 9649208 Free PMC article.
-
Interferon gamma stimulation modulates the proteolytic activity and cleavage site preference of 20S mouse proteasomes.J Exp Med. 1994 Mar 1;179(3):901-9. doi: 10.1084/jem.179.3.901. J Exp Med. 1994. PMID: 8113682 Free PMC article.
-
Unsupervised Mining of HLA-I Peptidomes Reveals New Binding Motifs and Potential False Positives in the Community Database.Front Immunol. 2022 Mar 21;13:847756. doi: 10.3389/fimmu.2022.847756. eCollection 2022. Front Immunol. 2022. PMID: 35386688 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Research Materials
