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Clinical Trial
. 2007 Feb;36(2):110-6.
doi: 10.1111/j.1600-0714.2007.00478.x.

A combined treatment regimen for desquamative gingivitis in patients with oral lichen planus

R Guiglia  1 , C Di Liberto, G Pizzo, L Picone, L Lo Muzio, P D Gallo, G Campisi, M D'Angelo
Affiliations
Clinical Trial

A combined treatment regimen for desquamative gingivitis in patients with oral lichen planus

R Guiglia et al. J Oral Pathol Med. 2007 Feb.

Abstract

Background: Chronic desquamative gingivitis (DG) is a condition characterized by erythema, ulceration, and desquamation of the free and attached gingiva, usually expression of a district-systemic disease, such as oral lichen planus (OLP).

Methods: A combined protocol of oral hygiene and topic corticosteroid therapy was applied in 30 patients with DG associated with OLP. Plaque index (PI) and bleeding on probing (BoP) were evaluated at baseline and after 3 months.

Results: PI scoring was significantly lower after treatment in anterior, posterior, and all sites (P < 0.0001) as well as in vestibular and lingual ones (P < 0.0001 and P = 0.0001, respectively). BoP measures were found to be reduced significantly to 22.94% in a full-mouth evaluation (P < 0.0001; OR = 2.633; 95% CI: 2.2685-3.0561) as well as in each specific site (P < 0.0001).

Conclusion: This clinical trial validated the efficacy, in patients with DG associated with OLP, of a protocol based on professional oral hygiene and self-performed plaque control measures in improving of gingival health status.

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