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Review
. 2007 Jan;26(1):7-8.
doi: 10.1016/j.immuni.2007.01.003.

Early commitment: T cell progenitors in the blood

Howard T Petrie  1
Affiliations
Free article
Review

Early commitment: T cell progenitors in the blood

Howard T Petrie. Immunity. 2007 Jan.
Free article

Abstract

Thymic lymphopoiesis depends on blood-borne, marrow-derived progenitors, but characterization of these cells, and their lineage potentials, has been difficult. In this issue, Krueger and von Boehmer show some blood cells that are already T lineage restricted, suggesting that T lineage commitment can occur pre-thymically.

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