Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2007 Feb;104(2):421-4.
doi: 10.1213/01.ane.0000253668.10453.de.

Does ondansetron or granisetron prevent subarachnoid morphine-induced pruritus after cesarean delivery?

Sahar M Siddik-Sayyid  1 , Marie T Aouad, Samar K Taha, Mireille S Azar, Mona A Hakki, Romeo N Kaddoum, Viviane G Nasr, Vanda G Yazbek, Anis S Baraka
Affiliations
Randomized Controlled Trial

Does ondansetron or granisetron prevent subarachnoid morphine-induced pruritus after cesarean delivery?

Sahar M Siddik-Sayyid et al. Anesth Analg. 2007 Feb.

Abstract

Background: We compared the efficacy of granisetron and ondansetron for the prevention of subarachnoid morphine-induced pruritus after cesarean delivery.

Methods: The incidence of pruritus was assessed in parturients who were randomly allocated into Group G (granisetron 3 mg IV, n = 45), Group O (ondansetron 8 mg IV, n = 42), and Group S (saline IV, n = 42).

Results: The incidence of pruritus was not significantly different among the 3 groups (86.6% in Group S, 83.3% in Group O, and 88% in the Group G).

Conclusion: Neither prophylactic ondansetron nor granisetron reduced the incidence of subarachnoid morphine-induced pruritus when compared with the saline group.

PubMed Disclaimer

Publication types