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Comment
. 2007 Feb;8(2):119-20.
doi: 10.1038/ni0207-119.

Shaping a helper T cell identity

Harinder Singh
Comment

Shaping a helper T cell identity

Harinder Singh. Nat Immunol. 2007 Feb.

Abstract

Cell fate 'decisions' involving multipotential progenitors seem to be 'dictated' by threshold activities of lineage-determining transcription factors. Such 'decisions' are now shown to be reinforced by the induction of secondary transcription factors that act in concert with the primary regulators.

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