More promiscuity resulting in more tolerance
- PMID: 17242681
- DOI: 10.1038/ni0207-120
More promiscuity resulting in more tolerance
Abstract
Tolerance to self is engendered by multiple mechanisms. Lymph node stromal cells are now found to contribute to self-tolerance by their endogenous expression of peripheral tissue antigens.
Comment on
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Peripheral antigen display by lymph node stroma promotes T cell tolerance to intestinal self.Nat Immunol. 2007 Feb;8(2):181-90. doi: 10.1038/ni1427. Epub 2006 Dec 31. Nat Immunol. 2007. PMID: 17195844
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