Treg cells: guardians for life
- PMID: 17242683
- DOI: 10.1038/ni0207-124
Treg cells: guardians for life
Abstract
Regulatory T cells expressing the transcription factor Foxp3 are known to control autoreactivity during and subsequent to the development of the peripheral immune system. New evidence emphasizes the fact that those cells are constant and powerful guardians against the state of 'horror autotoxicus'.
Comment on
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Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice.Nat Immunol. 2007 Feb;8(2):191-7. doi: 10.1038/ni1428. Epub 2006 Nov 30. Nat Immunol. 2007. PMID: 17136045
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