[Association of I and II class HLA antigens with Cushing's syndrome]
[Article in
Russian]
- PMID: 1724274
Item in Clipboard
[Association of I and II class HLA antigens with Cushing's syndrome]
[Article in
Russian]
Klin Med (Mosk).
1991 Aug.
Abstract
Incidence of class I and II HLA antigens was studied in 69 patients suffering from Icenko--Cushing syndrome. Positive association was reported for antigens DRw53, DQw3, DR4, DR5, negative for antigen DR2. Antigen combinations DR5, DR7 and DR4, DR5 proved more prevalent. The risk to develop the disease rose 2-3-fold in case of HLA-DR5 phenotype occurrence with antigen DR4 or DR7. Association with DRw53 and DQw3 antigens showing wide specificity seemed most significant.
Similar articles
-
Structural relationships between the DR beta 1 and DR beta 2 subunits in DR4, 7, and w9 haplotypes and the DRw53 (MT3) specificity.J Immunol. 1986 Aug 1;137(3):934-40. J Immunol. 1986. PMID: 2424991
-
[Genetic approaches to Itsenko-Cushing disease].Ter Arkh. 1993;65(4):78-83. Ter Arkh. 1993. PMID: 8059414 Russian.
-
Molecular identifications of HLA-DR4, MT3, and TB21 antigens on HLA-DR4 homozygous B cell lines.J Immunol. 1984 Feb;132(2):574-7. J Immunol. 1984. PMID: 6418807
-
Genetics of RA: the HLA shared epitope hypothesis and its implications.Br J Rheumatol. 1991;30 Suppl 2:6-9. Br J Rheumatol. 1991. PMID: 1704274 Review. No abstract available.
-
The genetic control of human Ia alloantigens: a three-loci model derived from the immunochemical analysis of 'supertypic' specificities.Immunol Rev. 1982;66:5-37. doi: 10.1111/j.1600-065x.1982.tb00432.x. Immunol Rev. 1982. PMID: 6182090 Review. No abstract available.
Publication types
MeSH terms
Substances
LinkOut - more resources
Medical
Research Materials