Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1975 Nov-Dec;11(6):400-3.
doi: 10.1007/BF02616377.

Detection of bovine viruses in fetal bovine serum used in cell culture

A J Kniazeff, L J Wopschall, H E Hopps, C S Morris

Detection of bovine viruses in fetal bovine serum used in cell culture

A J Kniazeff et al. In Vitro. 1975 Nov-Dec.

Abstract

This investigation employed a viral screening method detect endogenous bovine virus contaminants in commercially supplied fetal bovine serum. Fifty-one lots of fetal bovine serum from 14 suppliers were examined. Over 30% of the lots tested were found to contain bovine viruses; they included bovine virus diarrhea virus, parainfluenza type3-like virus, bovine herpesvirus-1, bovine enterovirus type 4, and an unidentified cytopathogenic agent. Of the 51 lots, 20 had been pretested by the suppliers and were considered to be free of known viral contaminants. Our viral screening methods revealed that five of these pretested lots, or 25%, contained endogenous bovine viruses.

PubMed Disclaimer

References

    1. Nature. 1961 Apr 22;190:302-5 - PubMed
    1. In Vitro. 1971 Nov-Dec;7(3):174-89 - PubMed
    1. Natl Cancer Inst Monogr. 1968 Dec;29:123-32 - PubMed
    1. In Vitro. 1971 Nov-Dec;7(3):168-73 - PubMed

Publication types

MeSH terms