[Histopathology and morphometry of hematopoiesis in bone marrow of AIDS patients in comparison with patients with myelodysplastic syndrome]

Abstract

Hematological data and histopathological bone marrow findings were compared in 60 patients with acquired immune deficiency syndrome (AIDS), 40 patients with myelodysplastic syndrome (MDS) and concurrent inflammation, and 39 HIV-negative patients with severe inflammation. Results show that the hematologic, histologic, and morphometric findings in patients with AIDS have a closer resemblance to the findings in patients with severe inflammation than to those in patients with MDS. It is concluded, that the peripheral cytopenia frequently observed in AIDS-patients is rather a consequence of severe inflammation, than of ineffective hematopoiesis.