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. 1977 Oct;87(2):319-25.
doi: 10.1093/genetics/87.2.319.

Electrophoretic variation for x-chromosome-linked phosphoglycerate kinase (pgk-1) in the mouse

J T Nielsen  1 , V M Chapman
Affiliations

Electrophoretic variation for x-chromosome-linked phosphoglycerate kinase (pgk-1) in the mouse

J T Nielsen et al. Genetics. 1977 Oct.

Abstract

Electrophoretic variation for X-chromosome-linked phosphoglycerate kinase (PGK-1) has been found as a polymorphism in feral mice in Denmark. Males from feral sampling or from a variety of genetic crosses have only a single-banded phenotype of the variant PGK-1A type or of the PGK-1B type commonly found among inbred mice. By contrast, three phenotypes were observed among females; two homozygous single-banded types and a heterozygous double-banded type. The X-chromosome linkage of the Pgk-1 locus was determined from the mode of inheritance in F(1) and backcross generations and confirmed by the linkage of Pgk-1 and the X-linked markers Hq, Ta and Mo. Pgk-1 showed 29/122 recombinations with Hq, 5/185 with Ta and 0/108 recombinants with Mo. Based on these recombination data, a gene order of Hq-Ta-Pgk-1-Mo is suggested.

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References

    1. N Engl J Med. 1969 Mar 6;280(10):528-34 - PubMed
    1. Nature. 1961 Apr 22;190:372-3 - PubMed
    1. Genetics. 1967 Oct;57(2):331-46 - PubMed
    1. Nature. 1976 Feb 26;259(5545):665-7 - PubMed
    1. Am J Hum Genet. 1971 Jan;23(1):87-91 - PubMed