Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2007 Feb 1;9(3):533-6.
doi: 10.1021/ol0629869.

Stereoselective synthesis of the C(1)-C(19) fragment of tetrafibricin

Ricardo Lira  1 , William R Roush
Affiliations

Stereoselective synthesis of the C(1)-C(19) fragment of tetrafibricin

Ricardo Lira et al. Org Lett. .

Abstract

[reaction: see text] A stereoselective synthesis of the C(1)-C(19) fragment of tetrafibricin has been accomplished via a highly diastereoselective double allylboration reaction of 6-8 and an iodonium ion promoted urethane cyclization for the installation of the C(15) alkoxy function in 3.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Tetrafibricin Retrosynthetic Analysis.
Scheme 1
Scheme 1
Synthesis of Benzyl Carbamate 13
Scheme 2
Scheme 2
Synthesis of Aldehyde 16
Scheme 3
Scheme 3
Completion of the Synthesis of the C(1)-C(19) Fragment 3 of Tetrafibricin
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Kamiyama T, Umino T, Fujisaki N, Satoh T, Yamashita Y, Ohshima S, Watanabe J, Yokose K. J. Antibiot. 1993;46:10392. - PubMed
    1. Kamiyama T, Itezono Y, Umino T, Satoh T, Nakayama N, Yokose K. J. Antibiot. 1993;46:1047. - PubMed
    1. Satoh T, Kouns WC, Yamashita Y, Kamiyama T, Steiner B. Biochem. Biophys. Res. Commun. 1994;204:325. - PubMed
    1. Satoh T, Yamashita Y, Kamiyama T, Arisawa M. Thromb. Res. 1993;72:401. - PubMed
    1. Kobayashi Y, Czechtizky W, Kishi Y. Org. Lett. 2003;5:93. - PubMed

Publication types