Heavy tools for genome mining
- PMID: 17254946
- DOI: 10.1016/j.chembiol.2007.01.001
Heavy tools for genome mining
Abstract
In this issue of Chemistry & Biology, Gross et al. report development of a novel genome mining method for isolating products of orphan biosynthetic gene clusters, and the application of this method to the isolation of orfamide A, a novel cyclic lipopeptide.
Comment on
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The genomisotopic approach: a systematic method to isolate products of orphan biosynthetic gene clusters.Chem Biol. 2007 Jan;14(1):53-63. doi: 10.1016/j.chembiol.2006.11.007. Chem Biol. 2007. PMID: 17254952
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