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. 2007 Jan;76(1):42-7.

Seven years of regional malaria control collaboration--Mozambique, South Africa, and Swaziland

Brian L Sharp  1 , Immo Kleinschmidt, Elisabeth Streat, Rajendra Maharaj, Karen I Barnes, David N Durrheim, Frances C Ridl, Natasha Morris, Ishen Seocharan, Simon Kunene, Jacobus J P LA Grange, Jotham D Mthembu, Francois Maartens, Carrin L Martin, Avertino Barreto
Affiliations

Seven years of regional malaria control collaboration--Mozambique, South Africa, and Swaziland

Brian L Sharp et al. Am J Trop Med Hyg. 2007 Jan.

Abstract

The Lubombo Spatial Development Initiative is a joint development program between the governments of Mozambique, Swaziland, and South Africa, which includes malaria control as a core component of the initiative. Vector control through indoor residual spraying (IRS) was incrementally introduced in southern Mozambique between November 2000 and February 2004. Surveillance to monitor its impact was conducted by annual cross-sectional surveys to assess the prevalence of Plasmodium falciparum infection, entomologic monitoring, and malaria case notification in neighboring South Africa and Swaziland. In southern Mozambique, there was a significant reduction in P. falciparum prevalence after the implementation of IRS, with an overall relative risk of 0.74 for each intervention year (P < 0.001), ranging from 0.66 after the first year to 0.93 after the fifth intervention year. Substantial reductions in notified malaria cases were reported in South Africa and Swaziland over the same period. The success of the program in reducing malaria transmission throughout the target area provides a strong argument for investment in regional malaria control.

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Figures

Figure 1
Figure 1
Map of the LSDI malaria control zones and location of sentinel sites. BWA, Botswana; MOZ, Mozambique; NAM, Namibia; ZAF, South Africa; SWZ, Swaziland; ZWE, Zimbabwe.
See this image and copyright information in PMC

References

    1. Sharp BL, Craig MH, Mnzava A, Curtis B, Maharaj R, Kleinschmidt I. [Accessed October 19, 2006];Review of malaria in South Africa. 2001 Available at http://www.hst.org.za/uploads/files/chapter18_00.pdf.
    1. Gallup JL, Sachs JD. The economic burden of malaria. Am J Trop Med Hyg. 2001;64(1–2 Suppl):85–96. - PubMed
    1. Sharp BL, le Sueur D. Malaria in South Africa–the past, the present and selected implications for the future. S Afr Med J. 1996;86:83–89. - PubMed
    1. Mabaso MLH, Sharp BL, le Sueur D, Lengeler C. Historical review of malaria control in southern African with emphasis on the use of indoor residual house spraying. Trop Med Int Health. 2004;9:846–856. - PubMed
    1. Maharaj R, Mthembu DJ, Sharp BL. The impact of the reintroduction of DDT on malaria transmission in KwaZulu-Natal, South Africa. S Afr Med J. 2005;95:871–874. - PubMed

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