Antifungal drug susceptibility profile of Pichia anomala isolates from patients presenting with nosocomial fungemia
- PMID: 17261632
- PMCID: PMC1855522
- DOI: 10.1128/AAC.01038-06
Antifungal drug susceptibility profile of Pichia anomala isolates from patients presenting with nosocomial fungemia
Abstract
In vitro susceptibility of 58 isolates of Pichia anomala to five antifungal drugs using two broth microdilution methods (CLSI and EUCAST) was analyzed. Low susceptibility to itraconazole was observed. Fluconazole, voriconazole, amphotericin B, and caspofungin showed good antifungal activity, although relatively high drug concentrations were necessary to inhibit the isolates.
References
-
- Alter, S. J., and J. Farley. 1994. Development of Hansenula anomala infection in a child receiving fluconazole therapy. Pediatr. Infect. Dis. J. 13:158-159. - PubMed
-
- Aragão, P. A., I. C. Oshiro, E. I. Manrique, C. C. Gomes, L. L. Matsuo, C. Leone, M. L. Moretti-Branchini, and A. S. Levin. 2001. Pichia anomala outbreak in a nursery: exogenous source? Pediatr. Infect. Dis. J. 20:843-848. - PubMed
-
- Bakir, M., N. Cerikcioglu, A. Tirtir, S. Berrak, E. Ozek, and C. Canpolat. 2004. Pichia anomala fungaemia in immunocompromised children. Mycoses 47:231-235. - PubMed
-
- Barchiesi F., A. M Tortorano, L. F. Di Francesco, M. Cogliati, G. Scalise, and M. A. Viviani. 1999. In vitro activity of five antifungal agents against uncommon clinical isolates of Candida spp. J. Antimicrob. Chemother. 43:295-299. - PubMed
-
- Barchiesi, F., A. M. Tortorano, L. F. Di Francesco, A. Rigoni, A. Giacometti, E. Spreghini, G. Scalise, and M. A. Viviani. 2005. Genotypic variation and antifungal susceptibilities of Candida pelliculosa clinical isolates. J. Med. Microbiol. 54:279-285. - PubMed
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