doi: 10.1007/978-3-7091-9175-0_2.
Molecular aspects of the neuronal noradrenaline transporter
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- PMID: 1726219
- DOI: 10.1007/978-3-7091-9175-0_2
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Molecular aspects of the neuronal noradrenaline transporter
J Neural Transm Suppl.
1991.
Abstract
The neuronal noradrenaline transporter was partially purified by means of low and high pressure liquid chromatography using anion exchange, gel filtration and lectin affinity columns. A protein characterized by a molecular weight of 50-53 kilodalton was enriched; it may represent the transporter or a component of it. In addition, a RNA fraction characterized by a mean size of 2 kilobases was isolated from PC12 rat phaeochromocytoma cells and from bovine adrenal medulla; this RNA fraction caused expression of the noradrenaline transporter after microinjection into Xenopus laevis oocytes.
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