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Case Reports
. 2007 Jan;74(1):79-82.
doi: 10.1007/s12098-007-0033-y.

Beneficial effects of rituximab therapy for systemic lupus erythematosus

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Case Reports

Beneficial effects of rituximab therapy for systemic lupus erythematosus

Shina Menon et al. Indian J Pediatr. 2007 Jan.

Abstract

We report an 11-yr-old girl with systemic lupus erythematosus (SLE) with recurrent flares of skin and systemic manifestations, which were poorly controlled with conventional therapy. Treatment with rituximab, a monoclonal antibody against CD20, was associated with remission of symptoms and a steroid sparing effect that persisted for more than 9 months. Therapy with rituximab appears promising in subjects with SLE.

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