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. 2007 Feb;55(2):304-7.
doi: 10.1248/cpb.55.304.

New diphenyl ethers from the insect pathogenic fungus Cordyceps sp. BCC 1861

Taridaporn Bunyapaiboonsri  1 , Seangaroon Yoiprommarat, Kamolphan Intereya, Kanokarn Kocharin
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Free article

New diphenyl ethers from the insect pathogenic fungus Cordyceps sp. BCC 1861

Taridaporn Bunyapaiboonsri et al. Chem Pharm Bull (Tokyo). 2007 Feb.
Free article

Abstract

Two novel diphenyl ether glycosides and a new diphenyl ether, cordyol A-C (1-3), were isolated from the insect pathogenic fungus Cordyceps sp. BCC 1861. Structures of these compounds were elucidated by NMR and MS spectral analyses. Cordyol C (3) exhibited significant anti-HSV-1 activity with an IC50 value of 1.3 microg/ml, and cytotoxic activity against BC and NCI-H187 cancer cell lines with IC50 values of 8.65 and 3.72 microg/ml, respectively. Cordyol A (1) displayed weak antimycobacterial activity with a MIC value of 100 microg/ml.

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