Review
[Application of BMP to bone repair]
[Article in
Japanese]
Affiliations
- PMID: 17272885
Item in Clipboard
Review
[Application of BMP to bone repair]
[Article in
Japanese]
Clin Calcium.
2007 Feb.
Abstract
Bone regeneration process involves upregulation of various bone morphogenetic proteins (BMPs) and their receptors, and several lines of evidence have demonstrated that BMP signaling plays a crucial role in bone regeneration. Recent research using conditional knockout mice of BMP-2 in limb revealed the essential role of BMP-2 during bone regeneration. Recombinant human BMPs and gene therapy of BMPs have been successfully applied to bone repair including application to dental implant.
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